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Overdose is one of the most serious challenging risk that people using drugs face. Especially after release from prison or hospitalisation they face an serious increased risk of overdosing. Naloxon is a safe antidote and highly effective intervention to an opioid overdose that can easily be administered by lay people.

The article "Power in a bottle: expanding Naloxon access" decribes various ways to increase the availability and access to the life saving medication Naloxon.


There is limited research on overdosis and Naloxone interventions in prison settings. A good resource from the UK describing a randomised control pilot trial on Naloxone after release is from Mahesh Parmar et al, 2016.
The study adds research-based findings on the growing consensus that take-home Naloxon at prison release can prevent prevent overdose deaths and that the intervention is a significant opportunity to prevent overdose among PWID.

Training and manuals

A usefull training manual is published by EHRN in 2014, The elalborte training manual written by Danny Morris and Gill Bradbury gives a broad overview of overdose prevention programming upon release in prison. The manual includes different modules and sessions that can be adjusted tot he local context. The comprehensive manual also includes templates, resources and PPT for the training. 

Toolkit: Guidelines for naloxone provision upon release from prison and other custodial settings

Guidelines for naloxone provision upon release from prison and other custodial settings - a hands-on toolkit for policymakers and practitioners on how to set up and run naloxone programmes for overdose prevention upon release from prison and other custodial settings.

The toolkit aim at providing hands-on recommendations for policymakers and practitioners from prison health services on how to promote, initiate and manage interventions related to overdose prevention through naloxone programs and how to organise related training and capacity building.

Kirsten Horsburgh from the Scottish Drugs Forum, author of the guidelines, analysed information and literature available from a number of European countries as well as relying on the Scottish national naloxone programme experience, with particular reference to interventions focusing on people leaving prison.

The French version of this toolkit is available here: Naloxone à la sortie de prison. Recommandations pour la mise à disposition de la naloxone à la sortie de prison et des autres lieux de privation de liberté.