Synthetic Opioid key responses
- Mapping evidence-based key responses to synthetic opioids and their implementation strategies
- Field-tested Toolkit with seven implementation guides
Direct-acting antiviral treatment for hepatitis C among people who use or inject drugs: a systematic review and meta-analysis
The research team compiled deidentified questions during field enrollments. Results. FAQs were reviewed and categorized into four major domains, including risk/prevention, screening, treatment, and reinfection. FAQs were addressed by a team of medical and public health professionals, using the most current research and recommendations.
Protective effect of coffee consumption on all-cause mortality of French HIV-HCV co-infected patients, Maria P. Carrieri, et al.
Coffee has anti-inflammatory and hepatoprotective properties but its effect on mortality risk has never been investigated in patients co-infected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV). This study shows that elevated coffee consumption (≥3 cups/day) halves all-cause mortality risk in patients co-infected with HIV-HCV. The benefits of coffee extracts and supplementing dietary intake with other anti-inflammatory compounds need to be evaluated in this population.
Hepatitis C Virus Diagnosis and the Holy Grail
It is not often the world has the opportunity to turn a public health crisis into a good news story. The development of oral, highly effective, pangenotypic direct-acting antivirals (DAAs) has now paved the way to cure the 71 million people estimated to be living with chronic hepatitis C virus (HCV) infection globally. This report highlights improving access to rapid, simple, and affordable HCV diagnostics is critical to achieve global HCV elimination.
EASL Commission on liver diseases in Europe: overcoming unmet needs, stigma, and inequities
The increasing health burden, the advent of novel and costly therapies, and the changing epidemiology demand innovative approaches and solutions for patients with liver diseases in European countries, which also face major demographic changes. By working with governmental and non-governmental organisations, such strategies must overcome cultural, ethical, and lifestyle barriers to vaccines and other preventive measures for obesity and alcohol consumption. F
Has Access to Hepatitis C Virus Therapy Changed for Patients With Mental Health or Substance Use Disorders in the Direct-Acting-Antiviral Period? Jain et, al
Direct-acting antivirals (DAA) for hepatitis C virus (HCV) became available in 2014, but the role of mental health or substance use disorders (MH/SUD) on access to treatment is unknown. The objective of this study was to examine the extent and predictors of HCV treatment in the pre-DAA and post-DAA periods in four large, diverse health care settings in the United States.
Action plan for the health sector response to viral hepatitis in the WHO European Region
This very first Action plan for the health sector response to viral hepatitis in the WHO European Region has been developed through a truly inclusive consultative approach. It draws on the expertise of an advisory committee and has benefited from the input of Member States, major partners and civil society, including patient organizations which represent the people who live with viral hepatitis in Europe.
Global, regional, and country-level coverage of interventions to prevent and manage HIV and hepatitis C among people who inject drugs: a systematic review
A country-level, regional, and global estimates of coverage of NSP,
OST, HIV testing, ART, and condom programmes for PWID
Achieving hepatitis C elimination in Europe – To treatment scale-up and beyond
The implication of this work is that for many countries the elimination of hepatitis C as a public health threat is not going to happen by chance. A number of barriers need to be overcome, requiring a focused effort from governments and health services
Increases in Acute Hepatitis C Virus Infection Related to a Growing Opioid Epidemic and Associated Injection Drug Use, United States, 2004 to 2014. Zibbell et al.
These findings strongly suggest that the national increase in acute HCV infection is related to the country's opioid epidemic and associated increases in IDU.
Interim impact evaluation of the hepatitis C virus elimination program in Georgia
The Georgia HCV elimination program has accomplished an impressive scale up of treatment, which has already impacted on prevalence and incidence, and averted deaths due to HCV. However, extensive scale up is needed to achieve a 90% reduction in prevalence by 2020.
